The best Side of cees dekker
The best Side of cees dekker
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Working with solitary-molecule optical and AFM imaging and power-spectroscopy strategies, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our study interests consist of:
You regularly become involved in discussions about science and religion. You might have also created quite a few publications on the topic. Don’t you imagine that sooner or later We're going to know every little thing Which God’s position will probably be about?
[Laughs] ‘It absolutely was unquestionably an awesome hazard! At the time, I had been very well informed that it could go Erroneous Which I could grow to be much less effective, but I just ignored that. Curiosity has normally been my strongest driving drive. And by chance all of it worked out.’
Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
What distinguishes biology from chemistry is the fact these elements alongside one another make up a residing procedure. The key of reported daily life, I think, lies while in the interactions, the interplay of All those molecules. The big problem regarding the origin of everyday living continues to be unanswered. How did we at any time evolve from easy molecules in the very advanced systems we see nowadays? We do not know. I want to work on These types of big, open issues.’
Stream-pushed rotary motors which include windmills and water wheels drive practical processes in human Culture. While samples of such rotary motors also function prominently in cell biology, their synthetic building with the nanoscale has remained complicated. Here we demonstrate movement-driven rotary motion of a self-organized DNA nanostructure which is docked onto a nanopore in a thin strong-state membrane. An elastic DNA bundle self-assembles into a chiral conformation upon phoretic docking onto the solid-state nanopore, and subsequently shows a sustained unidirectional rotary movement of up to twenty rev s−one.
‘Yes, I recognize people today have been astonished at time. At the conclusion of the nineties, After i was in my forties, I ceesdekker was Professor of Molecular Electronics and I've to confess that it had become a little bit bored, I didn’t learn Considerably anymore. The field went a lot more into the applying facet, how you may combine nanotubes into Digital circuits.
Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-producing procedure
‘The idea that There exists this kind of detail as being a starting, a huge bang, is now a fascinating signpost to think about that there was a creator. But a lot more normally, and on The idea of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is usually a naturalistic worldview: fundamentally, you will find only atoms and organic forces that we will measure.
Afterwards we spoke yet again briefly because Dekker felt that our discussion of his faith speedily grew to become purely philosophical, Whilst it also concretely assists him in his operate.
Developments in nanotechnology while in the nineties manufactured making Digital products from solitary molecules a probability. Cees Dekker recounts how his staff made a place-temperature transistor based upon one carbon nanotube.
2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with particular person solitary-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; initial biophysics characterization of your mechanical Homes of double-stranded RNA; and first solitary-molecule study of DNA translocation by a restriction-modification enzyme.